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home>US Stocks>Spruce Biosciences
SPRB
Spruce BiosciencesHealthcare
$42.58$-70.08 (-62.20%)in 1 year
As on 13 Nov 2026 at 02:29NASDAQ
52 Week Low: $38.0652 Week High: $127.90

Spruce Biosciences Share Price Today

Spruce Biosciences opened lower at $46.00, compared with its previous close of $46.20. In the last trading session, the stock traded between $42.09 and $46.00. It showed a downward intraday trend.

Return calculator

Time Period

An investment of $100 made 5 years ago in Spruce Biosciences is now worth

$ 12.90

Resulting in a loss of

$ 87.10 (87.10%)

Invest with $1

Note: Past profits do not guarantee future returns.

Analyst Overview

Buy

Rating from 5 Analysts

Buy
100%
Hold
0%
Sell
0%

Markets Today

Today's Change

$-3.62 (-7.83%)

Day High

$46.00

Day Low

$42.09

Day Open

$46.00

Prev Close

$46.20

Volume

37,812

1W Return

-8.01%

1M Return

-1.05%

3M Return

-7.80%

6M Return

-24.50%

1Y Return

-62.20%

Fundamentals

Market Cap ($ Mn)

122

PE Ratio

-

PB Ratio

1.99

PEG Ratio

-

ROE

-185.15%

ROCE

-184.35%

EPS (TTM)

$-5.90

Investment Returns

1 Week

-8.01%

1 Month

-1.05%

3 Months

-7.80%

6 Months

-24.50%

9 Months

-48.51%

Financials

Quarterly
All values in $ Mn
0.0

Mar 25
0.0

Jun 25
0.0

Sep 25
0.0

Dec 25
0.0

Mar 26
0.0

Jun 26

Updates

9Nov

Spruce Biosciences Q3FY26 Results: Loss per share narrows 41.63% YoY

Net loss widened to $24.0 million in Q3FY26 from $8.2 million in Q3FY25. Loss per share narrowed 41.63% YoY to $8.51 from $14.58. R&D expenses surged to $18.1 million from $5.0 million YoY. Cash reserves increased to $87.7 million, funding operations into H2 2027.

3 days ago
26Aug

Spruce Biosciences launches MPS3BStudy.com for TA-ERT programs

Spruce Biosciences launched MPS3BStudy.com for families to register interest in TA-ERT programs. Expanded Access Program and TrAnsform study expected to initiate in Q4 2026. Programs target children with Sanfilippo Syndrome Type B, an ultra-rare neurodegenerative disease. TA-ERT has prior safety data from 22 individuals across three clinical studies.

2mo ago
12Aug

Spruce Biosciences Q2 Results: EPS Misses Estimate, Losses Widen 91% YoY

Spruce Biosciences Inc reported Q2 EPS of $(6.68), missing the $(5.80) estimate by 15.17%. Losses widened 90.86% YoY from $(3.50), signaling deteriorating profitability and higher-than-expected operational costs.

3mo ago
3Aug

Spruce Biosciences appoints Jessica Cohen Pfeffer as clinical development VP

Spruce Biosciences appoints Jessica Cohen Pfeffer as VP of Clinical Development to lead efforts for its lead candidate TA-ERT. She brings extensive experience in rare pediatric neurodegenerative disorders from BioMarin. She received an inducement award of 3,800 RSUs vesting over four years.

3mo ago
13Jul

B. Riley initiates coverage on Spruce Biosciences with Buy rating

B. Riley Securities analyst Madison El-Saadi initiates coverage on Spruce Biosciences with a Buy rating and a $160 price target, indicating a positive outlook.

4mo ago
9Jul

Spruce Biosciences CEO to present at B. Riley summit in Boston

Spruce Biosciences, Inc. announced that CEO Javier Szwarcberg will present at the B. Riley Securities 2026 Mind, Muscle & Vision Healthcare Summit on July 16, 2026, in Boston. The company focuses on therapies for neurological disorders, with its lead candidate TA-ERT targeting MPS IIIB. Investors must contact B. Riley Securities to arrange meetings.

4mo ago

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