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SYRE
Spyre TherapeuticsHealthcare
$95.56+$71.73 (+301.01%)in 1 year
as on 30 Oct 2026 at 22:36NASDAQ
52 Week Low: $21.1552 Week High: $110.18

Spyre Therapeutics Share Price Today

Spyre Therapeutics opened lower at $96.78, compared with its previous close of $98.96. In the last trading session, the stock traded between $95.39 and $98.96. It showed a downward intraday trend.

return calculator

Time Period

An investment of $100 made 3 years ago in Spyre Therapeutics is now worth

$ 659.03

giving a profit of

$ 559.03 (559.03%)

invest with $1

Note: Past profits do not guarantee future returns.

Analyst Overview

Buy

Rating from 14 Analysts

Buy
100%
Hold
0%
Sell
0%

Markets Today

Today's Change

$-3.40 (-3.44%)

Day High

$98.96

Day Low

$95.39

Day Open

$96.78

Prev Close

$98.96

Volume

2,71,672

1W Return

3.52%

1M Return

12.72%

3M Return

-2.31%

6M Return

32.93%

1Y Return

301.01%

Fundamentals

Market Cap ($ Mn)

8,819

PE Ratio

-

PB Ratio

8.34

PEG Ratio

-

ROE

-42.01%

ROCE

-33.52%

EPS (TTM)

$-0.41

Investment Returns

1 Week

3.52%

1 Month

12.72%

3 Months

-2.31%

6 Months

32.93%

9 Months

184.57%

Financials

Quarterly
All values in $ Mn
0.0

Mar 25
0.0

Jun 25
0.0

Sep 25
0.0

Dec 25
0.0

Mar 26
0.0

Jun 26

Updates

19Oct

BTIG reiterates Buy rating on Spyre Therapeutics with $121 target

BTIG reiterates a Buy rating on Spyre Therapeutics. Price target maintained at $121 per share. Analyst Julian Harrison leads the coverage recommendation.

10 days ago
6Oct

Spyre Therapeutics prices $350M offering at $85 per share

Priced public offering at $85.00 per share. Raised approximately $350.0 million in gross proceeds. Sold 4,117,648 common shares. Funds to advance SPY072 for hidradenitis suppurativa. Underwriters have option for additional $52.5 million.

24 days ago
3Oct

Spyre Therapeutics grants inducement awards to two employees

Approved 21,424 stock options and 6,604 RSUs for two non-executive employees. Stock options have an exercise price of $89.93 and a 10-year term. Awards were granted under the 2018 Equity Inducement Plan per Nasdaq rules. Options vest over four years; RSUs vest on quarterly calendar anniversaries.

27 days ago
1Oct

BTIG reiterates Buy on Spyre Therapeutics, holds $121 target

BTIG reiterated a Buy rating on Spyre Therapeutics. Price target maintained at $121 per share. Analyst Julian Harrison issued the rating update.

29 days ago
5Sep

Spyre Therapeutics grants equity inducement awards to employee

Spyre Therapeutics granted 2,106 stock options and 745 RSUs to a non-executive employee. Stock options carry an exercise price of $88.50, matching the Sept 1 closing price. Awards vest over time based on continuous service, with options having a 10-year term. Grants were approved under the 2018 Equity Inducement Plan to secure employment.

1mo ago
26Aug

Spyre Therapeutics RA data misses internal bar; shares fall 12%

Spyre Therapeutics reported Phase 2 RA data for SPY072 showing statistical significance but missing internal monotherapy thresholds. Shares fell 12.33% to $94.12 following the disclosure that efficacy did not meet the bar for prioritization. Low dose showed significant benefit on primary endpoint DAS28-CRP vs placebo at Week 12. High dose showed nominal significance on secondary ACR20 endpoint; low dose on exploratory ACR50. Company maintains focus on combination therapies and other autoimmune indications.

2mo ago

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